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CASE REPORT

Delayed Type Hypersensitivity Towards Cosmetic Hyaluronic Acid Dermal Filler: A Case Report

Amanda Hong Chzi Ann, Deirdre Foo Hui Shan, Nurul Farhana Jahufar, Kenneth Wong Chen Fei, Prashanth Krishna A/L Ragunathan, Nurulhuda Haironi

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Volume 3, Issue 2
August 2023
Pages 13 - 18

Abstract: At the present time, the most common nonsurgical procedure in the aesthetic field are hyaluronic acid (HA) dermal fillers. It is appealing to many injectors as they are reversible with hyaluronidase and are generally well tolerated. However, there are several case studies which report hypersensitive reactions weeks after HA filler injections. The exact pathophysiology is inconclusive, but many agree that patients’ biological factors, injection technique and variations in the properties of the fillers could potentially play a role. In this case report, we discuss our encounter with a 60-year-old Chinese lady who presented to us two weeks after lower face hyaluronic acid filler injections with generalised pruritic facial rash and oedema. A clinical diagnosis of atopic dermatitis was made and the symptoms resolved with systemic corticosteroids.

Keywords: Delayed hypersensitivity, Hyaluronic acid dermal fillers, Dermal filler injections

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